The antiphospholipid syndrome may present itself to virtually all medi
cal specialties. It can be as non-threatening as thrombophlebitis or m
ild thrombocytopenia or as severe as cerebral arterial infarct or the
so called ''catastrophic APS''. In order to diagnose it properly, it i
s important to be aware of its clinical manifestations and laboratory
peculiarities. The primary form of APS seems to be more common than th
e SLE related one. Because any artery or vein may be involved, the spe
ctrum of clinical manifestations of APS is so wide that they include v
irtually all medical specialties.