T. Kondoh et al., INCREASED HISTIDINE PREFERENCE DURING SPECIFIC ALTERATION OF RHYTHM OF ENVIRONMENTAL-TEMPERATURE STRESS IN RATS, Behavioral neuroscience, 110(5), 1996, pp. 1187-1192
It has been reported that specific alteration of rhythm of environment
al temperature (SART) stress induces various physiological changes. In
this study, changes in taste preference during SART stress were inves
tigated in rats. Rats were given free access to six amino acid solutio
ns, saline, and water in a choice paradigm. During SART stress, daily
food intake increased significantly by 50% whereas the rate of body we
ight gain decreased significantly to one third that observed during th
e prestress baseline period. In addition, consumption of histidine sol
ution increased significantly, whereas intakes of water, monosodium gl
utamate, saline, glycine, arginine, lysine, and threonine were unaffec
ted. Results suggest that a specific preference for histidine emerges
during SART stress, which may be related to the stress-induced changes
in the histamine turnover in the brain and peripheral tissues.