Nm. Resnick et al., MISDIAGNOSIS OF URINARY-INCONTINENCE IN NURSING-HOME WOMEN - PREVALENCE AND A PROPOSED SOLUTION, Neurourol. urodyn., 15(6), 1996, pp. 599-613
Because of the high prevalence of detrusor hyperactivity with impaired
contractility (DHIC) in incontinent institutionalized women, we postu
lated that: 1) single-channel cystometry, the most commonly used diagn
ostic test, would be inadequate when used alone but that 2) its accura
cy could be greatly enhanced by combining it with a previously-perform
ed stress test. To test the hypothesis, we used blinded comparison of
a clinical stress test and single-channel cystometry with multichannel
videourodynamic evaluation (criterion standard), a strategy designed
a priori. Subjects were 97 incontinent women who were considered repre
sentative of incontinent nursing home women nationally. With cystometr
y alone, 9 of 37 women with DHIC (24%) were misdiagnosed as stress-inc
ontinent vs. 1 of 25 with DH (P = .03). In each case, misdiagnosis was
due to failure to recognize low-pressure involuntary bladder contract
ions. Combining cystometry with the stress test improved diagnostic ac
curacy markedly. Of the 77% of women in whom the results of both tests
were congruent, all were correctly classified. When results of the tw
o tests were discordant, neither was superior. Significantly, no woman
with stress incontinence was missed by the two-test strategy, nor was
anyone with detrusor hyperactivity misclassified. We conclude that in
institutionalized elderly women, DHIC commonly mimics other types of
urinary tract dysfunction. Thus, single-channel cystometry alone is an
inadequate diagnostic test in this population. However, a strategy th
at combines cystometry with a clinical stress test can correctly class
ify the majority of such women and identify those in whom the diagnosi
s is less secure. Use of this simple strategy would facilitate correct
diagnosis and initial treatment of most institutionalized women witho
ut referral, and also enrich the referred population with those most l
ikely to benefit. Such an approach could significantly improve the app
roach to this costly and morbid condition. (C) 1996 Wiley-Liss, Inc.