A dynamic model has been developed for the size fractionation process
of gas-filled microspheres by flotation. The aim of this dynamic model
is to control the fractionation process in an Nycomed Imaging AS Info
son(TM) production plant. A general population balance is established
for the dispersed phase that is later simplified for the specific part
icle suspension and process equipment used. This dynamic model has bee
n tested against experimental data and shows a good correlation betwee
n the predicted and measured values. This paper describes both the phy
sical phenomena and the modeling method.