NEW OXYGENATED CEPHALOTAXUS ALKALOIDS FROM CEPHALOTAXUS-HARRINGTONIA VAR DRUPACEA

Authors
TAKANO I YASUDA I NISHIJIMA M HITOTSUYANAGI Y TAKEYA K ITOKAWA H
Citation
I. Takano et al., NEW OXYGENATED CEPHALOTAXUS ALKALOIDS FROM CEPHALOTAXUS-HARRINGTONIA VAR DRUPACEA, Journal of natural products, 59(12), 1996, pp. 1192-1195
Citations number
16
Categorie Soggetti
Chemistry,"Plant Sciences","Pharmacology & Pharmacy","Chemistry Medicinal
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
59
Issue
12
Year of publication
1996
Pages
1192 - 1195
Database
ISI
SICI code
0163-3864(1996)59:12<1192:NOCAFC>2.0.ZU;2-W
Abstract
Three oxygenated cephalotaxine ester-type alkaloids, 11 alpha-hydroxyh omodeoxyharringtonine (1), 11 beta-hydroxyhomodeoxyharringtonine (2) a nd 11 beta-hydroxydeoxyharringtonine (3) were isolated hom Cephalatoxu s harringtonia var. drupacea. Their structures were established by spe ctroscopic methods including 2D NMR and CD spectra,and their antileuke mic activity was evaluated using P-388 leukemia cells.