EFFECT OF SOME ORGANIC AMMONIUM-SALTS AND AMINE OXIDES IN THE SOS CHROMOTEST

The effect of two organic ammonium salts, (1-methyldodecyl)trimethylam monium bromide (ATDBr) and tetramethylammonium bromide (TMABr), as wel l as that of two amine oxides, (1-methyl-dodecyl)dimethylamine oxide ( ATDNO) and trimethylamine oxide (TMANO) on the induction of the SOS sy stem in Escherichia coli PQ 37 (SOS chromotest) was examined. The comp ound with the long alkyl chain in the molecule (ATDBr) showed genotoxi c activity in all concentrations tested. In the second group of the am phiphilic compounds tested, amine oxides, no effect of the length of t he alkyl chain upon the studied activity was ascertained.