ASSOCIATION OF PRIMARY RENAL NON-HODGKINS-LYMPHOMA WITH MESANGIOPROLIFERATIVE GLOMERULONEPHRITIS

A 27-year-old male developed nonoliguric renal failure, Renal biopsy o f the left kidney showed infiltration by a diffuse large-cell non-Hodg kin's lymphoma (NHL), Laparoscopy, Ci scans of the abdomen and thorax, and bone-marrow biopsy revealed no further manifestations of lymphoma , Primary renal NHL was diagnosed, The patient attained complete remis sion with cyclophosphamide, adriamycin, vincristine, and prednisone (C HOP) chemotherapy and remained disease-free for 13 years, Eight years after his first presentation, the patient developed acute oliguric ren al failure with nephrotic syndrome. Mesangioproliferative glomerulonep hritis Was diagnosed in a biopsy of the left kidney, Chronic hemodialy sis was required until cadaver kidney transplantation was successfully performed 5 years later. Although the association of NHL and glumerul onephritis has been described several times before, to our knowledge t his is the first report of glomerulonephritis in primary renal lymphom a. (C) 1996 Wiley-Liss, Inc.