In 1992, the National Institute on Aging (NIA) and the National Cancer
Institute (NCI) initiated a study to assess the prevalence of comorbi
d conditions in elderly patients with cancer. Seven cancer sites were
selected for the study: breast, cervix, ovary, prostate, colon, stomac
h, and urinary bladder. This report on similar to 7600 patients in the
study sample describes the NIA/NCI approach to developing information
on comorbidity in elderly patients and addresses the chronic disease
burden (i.e., comorbidity) and severity for six particular conditions:
arthritis, chronic obstructive pulmonary disease (COPD), diabetes, ga
strointestinal problems, heart-related conditions, and hypertension. D
ata on comorbidity were collected by abstracting information from hosp
ital medical records. Patients were registered in six geographic areas
of the NCI Surveillance, Epidemiology, and End Results (SEER) Program
. A satisfied random sample of patients aged 55 to 64, 65 to 74, and 7
5 years or older with the index cancers were selected. Comorbidity dat
a were matched with data from the conventional SEER monitoring system.
Analyses showed that hypertension is the most prevalent condition and
is also much more common as a current management problem rather than
as history for the NIA/NCI SEER Study patients. Heart conditions varie
d slightly in the percentage of severity reported, but percentages for
all rumors remained within a range of 13 to 26% for current and past
categories. A similar range was observed for arthritis, with the highe
r percentage seen in the current problem category. For episodic compla
ints (e.g., gastrointestinal problems), a medical history was more com
mon, except for cancers that involve complaints associated with the ma
lignancy (e.g., colon and stomach cancers and, to a lesser extent, ova
rian cancer). COPD and diabetes were less prevalent. Analyses currentl
y under way will determine the impact of a patient's comorbidity burde
n on the cancer care continuum of diagnosis, treatment, and survival.
The broad and independent effects of chronic conditions, singly and in
combination, are being examined. (C) 1996 by Elsevier Science Inc.