Irrigation with antibiotic solutions is frequently used in penile pros
thesis surgery to avoid infection. We carried out a prospective study
to determine the degree of absorption of gentamicin after intracaverno
us irrigation in 10 patients who underwent penile implantation surgery
. All obtained values were below the toxic level of 10 mu g/ml and dec
reased gradually within a few hours. We concluded that highly concentr
ated gentamicin solutions could be used with safety for intracavernous
irrigation.