EVALUATION OF ISCHEMIA AFTER ESWL - DETECTION OF FREE OXYGEN RADICAL SCAVENGER ENZYMES IN RENAL PARENCHYMA SUBJECTED TO HIGH-ENERGY SHOCK-WAVES

To evaluate the degree of ischemic formation at the tissue level after high-energy shock wave (HESW) application in a time- and dose-depende nt manner, an experimental study in rabbits was performed. Following v arying numbers of HESWs (1,000-2,000-3,000 shock waves) under fluorosc opic localization, treated kidneys were removed, by assessing tissue c oncentrations of two different free-radical scavenger enzymes (superox ide dismutase and catalase) the degree of formation of free oxygen rad icals (i.e. ischemia) was evaluated. Evaluation of our results showed a statistically significant (p < 0.05) decrease in tissue scavenger en zyme levels (i.e. formation of free oxygen radicals) after 24 h follow ing HESW application. However, results obtained 7 days after ESWL demo nstrated disappearance of ischemia with normalization of tissue enzyme levels (p > 0.05).