STUDY OF THE INTERACTION FORCES IN HUMAN CD(4)LY

Authors
JANDOVA A KOBILKOVA J NEDBALOVA M SORFOVA J DOHNALOVA A TROJAN S POKORNY J
Citation
A. Jandova et al., STUDY OF THE INTERACTION FORCES IN HUMAN CD(4)LY, Bioelectrochemistry and bioenergetics, 41(2), 1996, pp. 181-185
Citations number
15
Categorie Soggetti
Biology
Journal title
Bioelectrochemistry and bioenergetics → ACNP
ISSN journal
03024598
Volume
41
Issue
2
Year of publication
1996
Pages
181 - 185
Database
ISI
SICI code
0302-4598(1996)41:2<181:SOTIFI>2.0.ZU;2-K
Abstract
The cluster formation of CD(4)Ly cells (a subpopulation of T lymphocyt es) in suspension was examined. CD(4)Ly cells were prepared from blood taken from cancer patients and from healthy counterparts (blood donor s). CD(4)Ly cells taken from cancer patients formed tightly bound clus ters in suspension with corresponding tumour antigen or LDH (lactic de hydrogenase) virus antigen. Cluster formation was a rare event in susp ensions with CD(4)Ly cells taken from healthy humans. Cluster formatio n coincides with decreased adherence of CD(4)Ly to solid state surface s and suggests strong mutual interaction between CD(4)Ly. A tentative theoretical explanation based on the Frohlich coherent vibration hypot hesis is given.