HYPERREACTIO LUTEINALIS COMPLICATING A NORMAL SINGLETON PREGNANCY

Hyperreactio luteinalis is a rare, usually self-limited syndrome with bilaterally enlarged ovaries containing multiple theca lutein cysts. I t is usually associated with gestational trophoblastic disease and/or pregnancies that have elevated maternal serum hCG levels. Hyperreactio luteinalis with maternal anasarca was diagnosed at 19 weeks in a spon taneously conceived gestation, in a 16-year-old primigravida. A second trimester termination for maternal respiratory decompensation seconda ry to pleural effusions and ascites was required. There was no evidenc e of trophoblastic disease on pathological examination of the products of conception. Hyperreactio luteinalis may be diagnosed prenatally by ultrasound, and intervention may be necessary for maternal indication s. Following termination of pregnancy, spontaneous resolution and regr ession of ovarian size may be expected.