VASCULITIS AND LYMPHOPROLIFERATIVE DISEASES

Vasculitis as a complication of lymphoproliferative diseases is relati vely uncommon. Cutaneous vasculitis is most commonly necrotizing and l eukocytoclastic. Granulomatous vasculitis occurs rarely with lymphopro liferative diseases, and even less commonly T-cell lymphocytic vasculi tis with eosinophilia, The most common systemic vasculitis is caused b y cryoglobulinemia, due to either lymphocytic lymphoma or Waldenstrom' s macroglobulinemia, Other unusual associations involving systemic vas culitides include polyarteritis nodosa and hairy cell leukemia, Wegene r's granulomatosis and Hodgkin's disease, granulomatous angiitis of th e central nervous system and lymphoma, temporal arteritis and lymphoma , and Henoch-Schonlein purpura and lymphoma. The vasculitis may predat e the diagnosis of the lymphoproliferative disease, and patients with vasculitis should be screened and monitored for lymphoproliferative di seases. Copyright (C) 1996 hy W.B. Saunders Company