IMPORTED CEREBRAL MALARIA COMPLICATED WITH GLUCOSE-6-PHOSPHATE-DEHYDROGENASE DEFICIENCY

Two cases of cerebral malaria imported from Guyana and Ghana are repor ted. These are the first cases of cerebral malaria diagnosed and treat ed in Trinidad and Tobago since malaria was eradicated. The management of both these cases was complicated because the patients' erythrocyte s were glucose-6-phosphate dehydrogenase-deficient, and by the occurre nce of blackwater fever, cerebral manifestations, renal impairment, hy perglycaemia and thrombocytopenia. The symptoms of cerebral malaria re solved following treatment with quinidine and doxycycline and quinidin e and clindamycin.