IDENTIFICATION OF FREE STEROLS IN CEREBRAL WHITE-MATTER OF RATS UPON OXYGEN DEFICIENCY USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY - 3-BETA-HYDROXYSTEROLS APPEARING IN TRACE AMOUNTS

Authors
PLAZIAK AS ADAMCZEWSKAGONCERZEWICZ Z DORSZEWSKA J
Citation
As. Plaziak et al., IDENTIFICATION OF FREE STEROLS IN CEREBRAL WHITE-MATTER OF RATS UPON OXYGEN DEFICIENCY USING GAS-CHROMATOGRAPHY MASS-SPECTROMETRY - 3-BETA-HYDROXYSTEROLS APPEARING IN TRACE AMOUNTS, Polish Journal of Chemistry, 70(11), 1996, pp. 1435-1441
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Polish Journal of Chemistry → ACNP
ISSN journal
01375083
Volume
70
Issue
11
Year of publication
1996
Pages
1435 - 1441
Database
ISI
SICI code
0137-5083(1996)70:11<1435:IOFSIC>2.0.ZU;2-K
Abstract
Continuing our study on lipids present in the myelin upon oxygen defic iency, we identified 3 beta-hydroxysterols appearing in trace amounts in the cerebral white matter of rats. Using a combination of gas chrom atography and mass spectrometry, the isomers of cholesterol and lanost erol as well as 24-methylcholesterol and 24-methyldesmosterol were ide ntified to be the trace components of total lipid fraction extracted f rom the myelin of rats.