G. Wen et al., THE PORCINE SKELETAL-MUSCLE RYANODINE RECEPTOR GENE STRUCTURE CODING REGION 1 TO 10,614 HARBORING 71 EXONS, Animal genetics, 27(5), 1996, pp. 297-304
The skeletal muscle ryanodine receptor (RYR1) belongs to a family of c
alcium release channels that are expressed in different tissues, The R
YR1 gene is one of the largest genes characterized, so far, containing
a 15253 nucleotide ORF in swine. To study the genomic organization of
the porcine skeletal muscle ryanodine receptor gene we have isolated
seven genomic fragments spanning 72 . 7 kb of chromosomal DNA of chrom
osome 6q12, This region harbours exons 1 to 71 coding for 3538 amino a
cids (69 . 6%) of the ryanodine receptor 1.