SYNTHESIS OF PODOPHYLLOTOXIN A-RING PYRIDAZINE ANALOG

Citation
E. Bertounesque et al., SYNTHESIS OF PODOPHYLLOTOXIN A-RING PYRIDAZINE ANALOG, Tetrahedron, 52(45), 1996, pp. 14235-14246
Citations number
104
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
ISSN journal
00404020
Volume
52
Issue
45
Year of publication
1996
Pages
14235 - 14246
Database
ISI
SICI code
0040-4020(1996)52:45<14235:SOPAPA>2.0.ZU;2-V
Abstract
Podophyllotoxin A-ring pyridazine analogue 3 has been constructed in n ine steps from (-)-podophyllotoxin. The Stille reaction was exploited to generate the key intermediate 4. Copyright (C) 1996 Elsevier Scienc e Ltd