IN-VITRO ACTIVITIES OF AZITHROMYCIN, CLARITHROMYCIN, AND OTHER ANTIBIOTICS AGAINST CHLAMYDIA-PNEUMONIAE

Authors
KUO CC JACKSON LA LEE A GRAYSTON JT
Citation
Cc. Kuo et al., IN-VITRO ACTIVITIES OF AZITHROMYCIN, CLARITHROMYCIN, AND OTHER ANTIBIOTICS AGAINST CHLAMYDIA-PNEUMONIAE, Antimicrobial agents and chemotherapy, 40(11), 1996, pp. 2669-2670
Citations number
18
Categorie Soggetti
Pharmacology & Pharmacy",Microbiology
Journal title
Antimicrobial agents and chemotherapy → ACNP
ISSN journal
00664804
Volume
40
Issue
11
Year of publication
1996
Pages
2669 - 2670
Database
ISI
SICI code
0066-4804(1996)40:11<2669:IAOACA>2.0.ZU;2-K
Abstract
The in vitro susceptibilities of Chlamydia pneumoniae isolates to macr olide, tetracycline, and quinolone antibiotics were determined. Tetrac ycline, clarithromycin, and erythromycin had the lowest MICs in the fi rst cell culture passage. Azithromycin required the lowest concentrati on for complete inhibition of inclusion formation on the second pass i nto antibiotic-free medium, likely reflecting its high intracellular c oncentrations.