INTERACTION OF SALMONELLA-TYPHI STRAINS WITH CULTURED HUMAN MONOCYTE-DERIVED MACROPHAGES

Authors
SIZEMORE DR ELSINGHORST EA ECK LC BRANSTROM AA HOOVER DL WARREN RL RUBIN FA
Citation
Dr. Sizemore et al., INTERACTION OF SALMONELLA-TYPHI STRAINS WITH CULTURED HUMAN MONOCYTE-DERIVED MACROPHAGES, Infection and immunity, 65(1), 1997, pp. 309-312
Citations number
19
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
65
Issue
1
Year of publication
1997
Pages
309 - 312
Database
ISI
SICI code
0019-9567(1997)65:1<309:IOSSWC>2.0.ZU;2-N
Abstract
Human monocyte-derived macrophages (MDM) provided this laboratory with a tool to develop a primary-cell assay for evaluating the relative vi rulence of newly constructed Salmonella typhi carrier strains, In this study, the interaction with and survival within MDM were compared for Delta aroA143-attenuated strains, wildtype virulent strains, and the current oral-vaccine strain, Ty21a.