R. Vyas et Jr. Ebright, TOXOPLASMOSIS OF THE SPINAL-CORD IN A PATIENT WITH AIDS - CASE-REPORTAND REVIEW, Clinical infectious diseases, 23(5), 1996, pp. 1061-1065
We present the case of a patient whose acute myelopathy almost complet
ely resolved with empirical therapy for toxoplasmosis, and we review t
hirteen previously reported cases of myelopathy thought to have been c
aused by Toxoplasma gondii in patients with AIDS. The most common symp
toms and abnormal physical findings were motor loss (usually parapares
is), bilateral sensory loss, urinary bladder dysfunction, and local pa
in. The majority of patients had magnetic resonance images that showed
abnormalities of the spinal cord and brain in association with positi
ve serology for Toxoplasma. Therapy for toxoplasmosis, when administer
ed soon after the onset of symptoms, has resulted in clinical and radi
ographic improvement in the conditions of patients with toxoplasmosis.