Four children and one adult with large myelomeningocele defects underw
ent operations for the repair of soft tissue defects. The tissue expan
sion technique was used. The silicone tissue expanders were inserted o
n one side or both sides of the lesion and inflated weekly by saline i
njections. The expanded skin and subcutaneous tissue allowed easy midl
ine closure of the defects. The results were very satisfactory.