INTRAOPERATIVE MITOMYCIN-C IN THE TREATMENT OF CICATRICIAL OBLITERATIONS OF CONJUNCTIVAL FORNICES

PURPOSE: To investigate whether the intraoperative use of topical mito mycin C improved the postoperative outcome in cases of cicatricial obl iteration of conjunctival fornices. METHODS: Ten eyes of five patients were subjected to surgical lysis of the synechiae followed by intraop erative application of 0.4 mg mitomycin C per milliliter of saline for 3 to 5 minutes. RESULTS: After a follow-up period of 12 to 19 months, no recurrence of synechiae was observed, the conjunctival fornices re mained open, and conjunctival overgrowths on the cornea did not recur. No adverse effect was observed. CONCLUSION: Intraoperative applicatio n of mitomycin C proved useful in the surgical treatment of cicatricia l shrinkage of conjunctival fornices.