TREATMENT OF BILATERAL CYTOMEGALOVIRUS RETINITIS WITH SUSTAINED-RELEASE GANCICLOVIR IMPLANTS IN A CHILD

Citation
Ds. Malley et al., TREATMENT OF BILATERAL CYTOMEGALOVIRUS RETINITIS WITH SUSTAINED-RELEASE GANCICLOVIR IMPLANTS IN A CHILD, American journal of ophthalmology, 122(5), 1996, pp. 731-732
Citations number
5
Categorie Soggetti
Ophthalmology
ISSN journal
00029394
Volume
122
Issue
5
Year of publication
1996
Pages
731 - 732
Database
ISI
SICI code
0002-9394(1996)122:5<731:TOBCRW>2.0.ZU;2-C
Abstract
PURPOSE: To report treatment of bilateral cytomegalovirus (CMV) retini tis in an 11-year-old girl with acquired immunodeficiency syndrome (AI DS). METHOD: Case report describing the use of intravitreal ganciclovi r sustained-release devices to treat CMV retinitis, involving zones 1 through 3, which progressed despite single and combination intravenous therapy with ganciclovir and foscarnet. RESULTS: Stabilization with n o active CMV retinitis was achieved after bilateral implantation of in travitreal sustained-release ganciclovir devices. There was no reactiv ation of the retinitis during the 5 months of follow-up. CONCLUSION: S ustained-release ganciclovir implants can be used to achieve local con trol of CMV retinitis in the pediatric patient.