Previous authors have described several pleural abnormalities on chest
radiography as being pathognomonic for asbestos exposure. We sought t
o determine the percentage of admissions and outpatient at a typical V
eteran's Affairs hospital with these findings, and research medical re
cords to verify the frequency at which patients having positive radiog
raphs were suspected either by clinical/occupational history or radiol
ogically to have had prior significant exposure to asbestos. Radiograp
hs of 1,212 consecutive patients were evaluated by a certified B reade
r, and the medical records as well as previous radiology reports of al
l positive patients were reviewed. Twenty-eight (2.3%) of the radiogra
phs had pleural abnormalities consistent with asbestos exposure, with
the patients, all male, ranging in age from 50 to 98 years (mean 75.6)
. Radiology reports described pleural plaques in only 12 of the 21 (57
%) cases with prior exams available; in only seven (33%) was an asbest
os etiology considered by the interpreting radiologist. The plaques we
re misdiagnosed in four instances as being indicative of other, unrela
ted pathology. A history of known dust exposure was expressed by only
five patients (18%). Eleven described working in occupations now known
to have a high incidence of exposure, but neither patient nor examini
ng physician expressed consideration of dust inhalation. In conclusion
, we have found that a significant percentage of patients in certain s
ubpopulations show radiographic evidence of asbestos exposure that may
be a harbinger of related pathology. Unfortunately, because of a low
index of suspicion, thorough environmental histories are often deferre
d, many radiographic changes are either not recognized or are misdiagn
osed, and these patients are not followed with the stringent protocols
they deserve. (C) 1996 Wiley-Liss, Inc.