CENTRAL GIANT-CELL GRANULOMA OF THE NOSE - CASE-REPORT AND REVIEW OF THE LITERATURE

Background: The central giant-cell (reparative) granuloma is an uncomm on bone lesion usually located in the mandible and maxilla. In contras t to giant cell tumors of the extra-craniofacial skeleton, the origin of this lesion is considered to be non-neoplastic, reactive, and trigg ered by trauma or inflammation. The tumor occurs mainly in young peopl e; they complain of regional indolent swelling of the jaw eventually l eading to loosening of the teeth. Case report: In the paper, the autho rs describe the unusual case of a central giant-cell granuloma in a yo ung male. Diagnostic procedures, adequate therapeutic approach, and an overview of differential diagnostic considerations are provided. Resu lts: The pedunculate tumor was removed surgically. In endoscopic contr ols no recurrent growth has been seen up to one year after removal. Co nclusions: Even though the giant-cell reparative granuloma is rare, it may also occur in the nasal cavity. Diagnosis is established by histo logic findings and the typical clinical appearance. Surgical removal i s the treatment of choice.