SYNTHESIS, AGGREGATION, AND BIOLOGICAL PROPERTIES OF A NEW CLASS OF GEMINI CATIONIC AMPHIPHILIC COMPOUNDS FROM ARGININE, BIS(ARGS)

In this work the synthesis and evaluation of a novel class of gemini b iocompatible surfactants from arginine with chemical, biological, and fundamental research applications are presented for the first time. In this strategy the environmental acceptability of the already biocompa tible single chain N-alpha-acyl arginine surfactants was reinforced by chemical dimerization order to obtain a gemini surfactant with a high physicochemical efficiency and a low toxicity. The application of the se molecules (with a very law intrinsic toxicity) in industrial proces ses could lead to a dramatic reduction in the concentration of surface active material for the same level of performance.