PULSE RADIOLYTIC INVESTIGATIONS ON THE REACTION OF THE 6-YL RADICALS OF URACILS WITH CU(II) AMINO-ACID COMPLEXES

The 6-yl-radicals of uracil and 1,3-dimethyluracil reduced Cu(II)-amin o acid complexes to produce Cu(I), that was proved by the formation of the complex with 2,9-dimethyl-1,10-phenanthroline (DMP). Rate constan ts for the reduction increased with increasing pH, ranging from 10(6) to 10(8) dm) mol(-1) s(-1). The kinetic pKa obtained for the complexes of glycine, alanine, and valine were all in agreement with pKa of the uracil-OH-adduct radical. The formation rate of Cu(I)-DMP complex sug gests the existence of the transient adduct between initial reactants. Copyright (C) 1996 Elsevier Science Ltd