Background: The aim of asthma therapy, i.e. the permanent elimination
of the patient's symptoms, is as a rule, achievable over the long-term
only with the aid of anti-inflammatory drugs. As well as medical, thi
s approach also has considerable economic implications. The comparativ
ely low compliance among asthmatics makes treatment in this contest al
l the more difficult. An alternative that presents itself is the use o
f combination preparations, a mixture of a long-term prophylactic and
a therapeutic agent. Patients and Methods: With the aid of standardise
d questionnaires, data were acquired from 216 patients and assigned to
subgroups in accordance with the degree of severity of the asthma. Th
e patients were treated in the offices of a total of 23 GPs and intern
ists selected at random from a complete list of all relevant practices
in Germany. The use: of resources, i.e. all diagnostic and therapeuti
c measures, was recorded retrospectively for a period of 1 year. In th
is way, all those resources of relevance to the health insurance carri
ers used during the observation period were identified. In addition to
direct costs, so-called indirect costs were also estimated. i.e. ill
the present study the productivity loss to the economy due to illness-
related absence from work. Results: The annual cost of treating adult
asthmatics was calculated to be DM 3,339 for level 1 severity, DM 5,26
0 for level 2 severity and DM 12,016 for level 3 severity. As the illn
ess progresses in particular the direct cost of inpatient care and the
indirect costs rise disproportionately. The yearly expenditure for wo
men sufferers is about DM 800 more than for male sufferers. The direct
cost of asthma treatment in children amounts to DM 2,950 for level 1,
DM 3,225 for level 2, and DM 4,811 for level 3, severity. Here, drug-
related costs in particular, rise significantly as the disease progres
ses. Conclusion: One of the results of the present study is the fact t
hat for asthma sufferers in general, there is a positive correlation b
etween average total costs and degree of severity. It may thus be post
ulated that preventive medical treatment of asthma that slows the proc
ession of the illness, together with appropriate patient instruction,
would have a positive effect on the total expenditure per patient. If,
for example, the appropriate use of drugs in combination with patient
instruction improved the compliance of asthmatics, lower treatment co
sts and a better quality of life for the patient could be expected.