3-ALKYLTHIOMETHYL-1-ETHYLIMIDAZOLIUM CHLORIDES - CORRELATION BETWEEN CRITICAL MICELLE CONCENTRATIONS AND MINIMUM INHIBITORY CONCENTRATIONS

Authors
PERNAK J SKRZYPCZAK A
Citation
J. Pernak et A. Skrzypczak, 3-ALKYLTHIOMETHYL-1-ETHYLIMIDAZOLIUM CHLORIDES - CORRELATION BETWEEN CRITICAL MICELLE CONCENTRATIONS AND MINIMUM INHIBITORY CONCENTRATIONS, European journal of medicinal chemistry, 31(11), 1996, pp. 901-903
Citations number
3
Categorie Soggetti
Chemistry Medicinal
Journal title
European journal of medicinal chemistry → ACNP
ISSN journal
02235234
Volume
31
Issue
11
Year of publication
1996
Pages
901 - 903
Database
ISI
SICI code
0223-5234(1996)31:11<901:3C-CBC>2.0.ZU;2-R
Abstract
3-Alkylthiomethyl-1-ethylimidazolium chlorides were prepared in high y ield via an S(N)1 reaction. The critical micelle concentration (CMC) v alues of studied chlorides were determined by surface tensiometry and the hydrophobicity index (HI) was calculated. The minimum inhibitory c oncentration (MIC) against various microorganisms such as cocci, rods, fungi and bacilli was studied. The quantitative relationship between the MIC, the CMC and the HI was calculated.