Employees of a communications firm experienced an acute outbreak of no
nspecific illness related to the workplace. Symptoms consisted primari
ly of coughing, throat irritation, shortness of breath and disorientat
ion. Fifty-one individuals sought emergency medical care, and the buil
ding was evacuated. A multidisciplinary team was assembled to investig
ate and resolve the problem. Investigation activities focused on three
major areas: epidemiology; environmental measurement; and mechanical
engineering. Results indicated that the outbreak was due to multiple f
actors working in concert. The inside of the air handling system was c
ontaminated with microbial growth and particulate matter; chemical pro
ducts were used throughout the building with little control over use p
atterns; and the HVAC system was not delivering acceptable quantities
of outdoor air to the employees' breathing zones. Two unusual events m
ay have triggered the employees' response. An unusual odor/taste was r
eported, and the outside air damper abruptly opened and closed, possib
ly dislodging particulate matter from inside the air handling system.
It appeared that psychosocial factors played an important role. Preven
tion of similar crises could be achieved by implementation of a policy
/procedure that addresses specific responsibilities, communications, p
reventive maintenance, acceptable outdoor air ventilation rates, and g
uidelines for reporting and investigation.