BLASTOMYCOSIS-LIKE PYODERMA (PYODERMA VEGETANS) RESPONDING TO ANTIBIOTICS AND TOPICAL DISODIUM CHROMOGLYCATE

Background. Blastomycosis-like pyoderma is a disorder of uncertain eti ology that has been described in association with a variety of underly ing conditions, including inflammatory and neoplastic pathologic condi tions and in association with a primary immunodeficiency state. The re sponse to therapy, antibiotics in particular, is said to be variable o r poor. Methods. We examined two patients with blastomycosis-like pyod erma in whom no underlying pathologic or immunologic abnormalities wer e found. We treated them with antibiotics according to bacterial resis tance tests. In the second case topical disodium chromoglycate was add ed. Results. Treatment cleared or markedly improved the lesions. Concl usions. Antibiotic treatment guided by susceptibility tests is recomme nded, The addition of topical disodium chromoglycate may be useful.