Our purpose is to examine how applicable current quality of life instr
uments are in advanced cancer. Quality of life (QOL) is difficult to d
efine and measure; it is a multidimensional, dynamic and subjective co
ncept. An acceptable QOL instrument for advanced disease should be sim
ple to administer and easy to explain, complete and analyse. In our vi
ew, the present instruments used in oncology do not serve the needs of
advanced cancer patients. Based on our review, we believe a single qu
estion posed on a linear or categorical scale should be used to assess
QOL in advanced cancer in preference to other available methods.