The paper presents a study of natural chrysotile and 15 samples modifi
ed using different temperature and pressure. The morphology, dimension
s, chemical composition, crystalline structure, and technologic charac
teristics of the samples studied were similar. The numbers of negative
ly charged centers on the surface of fibers were about the same in all
the samples. In two modified asbestos samples the number of positivel
y charged centers was less than in the native one. In these samples th
e energy of interaction of charged centers with macromolecules of roda
min and eozin was also less than in the sample of natural chrysotile.
It directly correlated with cytotoxicity and mutagenicity of them. The
principal possibility to decrease the biological activity of asbestos
lias been discussed.