ABCIXIMAB-ASSOCIATED PROFOUND THROMBOCYTOPENIA - THERAPY WITH IMMUNOGLOBULIN AND PLATELET TRANSFUSION

First-time abciximab administration was associated with acute profound thrombocytopenia in 4 of 575 consecutive patients. Therapy with plate let transfusion, but not intravenous immunoglobulin, was associated wi th a rapid and sustained increment in circulating platelet count and c linical hemostasis.