BAYESIAN FORECASTING IN PEDIATRIC POPULATIONS

Bayesian forecasting offers several important advantages for dosage in dividualisation in children, although, unlike for adults, its use in t his population is much lower. Indeed, currently Bayesian methods are u nderused in this patient population. The paucity of paediatric populat ion pharmacokinetic parameters, and the unavailability of specific cli nical pharmacokinetic software for the whole paediatric population, ar e the main limitations to the application of Bayesian methods in these patients. When these problems have been overcome, this approach will allow clinicians to achieve therapeutic concentrations more readily, f aster and more precisely, thus making the methodology highly attractiv e in the paediatric setting.