SQUAMOMETRY IN RATING THE EFFICACY OF TOPICAL CORTICOSTEROIDS IN ATOPIC-DERMATITIS

Squamometry is a non-invasive test allowing a reproducible rating of c utaneous xerosis including atopic dermatitis lesions. The method was u sed to compare the efficacy of proprietary topical corticosteroids in alleviating signs of atopic xerosis. Results: The steroid compounds an d their vehicles improve the texture of the stratum corneum at differe nt rates after treatment for 1 week. Some differences in efficacy may be explained by the nature of the vehicle, which enhances the basic ph armacological activity of the corticosteroid itself.