A NOVEL MODIFICATION OF THE RITTER REACTION USING TRIMETHYLSILYL CYANIDE

Authors
CHEN HG GOEL OP KESTEN S KNOBELSDORF J
Citation
Hg. Chen et al., A NOVEL MODIFICATION OF THE RITTER REACTION USING TRIMETHYLSILYL CYANIDE, Tetrahedron letters, 37(45), 1996, pp. 8129-8132
Citations number
6
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
37
Issue
45
Year of publication
1996
Pages
8129 - 8132
Database
ISI
SICI code
0040-4039(1996)37:45<8129:ANMOTR>2.0.ZU;2-N
Abstract
A new modification of the Ritter reaction using trimethylsilyl cyanide (Me(3)SiCN) is described, which converts their corresponding formamid es in high yields using a convenient procedure. The reaction condition s ana mechanism are discussed. In some cases, new formamides are synth esized which cannot be prepared by the classical Ritter reaction. Copy right (C) 1996 Elsevier Science Ltd