Purpose: We evaluated long-term results of patients with bladder exstr
ophy who underwent ureterosigmoidostomy. Materials and Methods: Of 4 w
omen and 23 men monitored at our institution 16 (59%) underwent primar
y diversion by ureterosigmoidostomy, while 11 (41%) underwent primary
bladder closure or an ileal conduit procedure before conversion to ure
terosigmoidostomy. Average followup after ureterosigmoidostomy was 17
years. Results: Significant upper urinary tract changes developed in 1
8% of the patients. Metabolic acidosis was well compensated in most pa
tients but 2 had problems with urinary retention leading to hyperammon
emia and acidosis. Of the 19 patients monitored with biennial colonosc
opy benign polyps were removed in 4. Daytime continence was achieved i
n 92% of cases and nighttime continence in 58%.Conclusions: Our experi
ence with ureterosigmoidostomy in children with bladder exstrophy has
been favorable through long-term followup. With proper imaging, metabo
lic surveillance, biennial colonoscopy and nonsteroidal anti-inflammat
ory drugs we offer ureterosigmoidostomy as a viable alternative for pa
tients with small bladders.