DIRECTING ALTERNATIVE SPLICING - CAST AND SCENARIOS

Authors
CHABOT B
Citation
B. Chabot, DIRECTING ALTERNATIVE SPLICING - CAST AND SCENARIOS, Trends in genetics, 12(11), 1996, pp. 472-478
Citations number
63
Categorie Soggetti
Genetics & Heredity
Journal title
Trends in genetics → ACNP
ISSN journal
01689525
Volume
12
Issue
11
Year of publication
1996
Pages
472 - 478
Database
ISI
SICI code
0168-9525(1996)12:11<472:DAS-CA>2.0.ZU;2-Q
Abstract
Recent progress in the study of alternative RNA splicing indicates tha t the interaction of RNA-binding proteins with specific target element s modulates splice site recognition and spliceosome assembly. The iden tity of splicing signals, the presence of modulating elements and diff erences in the distribution of RNA-binding proteins are key determinan ts involved in the tissue-specific regulation of splice site selection .