ABSORBABLE ADAMS-DEWEESE CAVAL CLIP - AN EXPERIMENTAL-STUDY

Adams-DeWeese caval clips have been shown to be effective in preventin g pulmonary embolism. However, the use of Teflon clips constitutes a p ermanent solution for this transient risk. We tested an absorbable cav al clip made of currently available synthetic biodegradable polymers i n five female Beagle dogs. The polymer used was PLA 96 containing 96% L lactic acid and 4% D lactic acid. After placement through a laparoto my, clips were routinely inspected and samples of the material were co llected at regular intervals between 3 and 19 months postoperatively. The characteristics of absorption of PLA 96 in the retroperitoneal spa ce were the same as those previously described in the literature. The clip retained its shape, rigidity, and effectiveness for 7 months. Com plete degradation of the clip took between 18 and 19 months. Absorptio n did not cause a major inflammatory reaction and had no thrombogenic effect. Given the small number of animals studied, these results must be considered preliminary.