The personality profile of 26 adult migraine patients from a large Swe
dish family with migraine and 87 controls were studied by means of Clo
ninger's seven-factor model of Temperament and Character (TCI; Tempera
ment and Character Inventory). For the diagnosis of migraine, a questi
onnaire, slightly modified to fit the criteria according to the AD HOC
committee on the classification of headaches of the International Hea
dache Society, was used. The TCI assesses four dimensions of temperame
nt, including novelty-seeking (NS), harm avoidance (HA), reward depend
ence (RD) and persistence (P), and three dimensions of character, incl
uding self-directedness (SD), co-operativeness (C) and self-transcende
nce (ST). Psychiatric morbidity did not differ between this family and
the general population. One migraine patient had double depression (d
ysthymia and recurrent depression) and one had a personality disorder.
No significant difference could be found in the higher order dimensio
ns of temperament (NS, HA, RD and P) and character (SD, C and ST) betw
een migraine patients and controls. However, on the subscale level, NS
showed a slightly higher average in NS1 (exploratory excitability) an
d a significantly higher (p=0.0448) average in NS2 (impulsivity) in mi
graine patients compared to controls. Somatic anxiety has been shown t
o be positively correlated with NS, and especially impulsivity. Our re
sults showed a tendency of this personality profile, and may suggest a
n association between migraine and somatic anxiety. Copyright (C) 1996
Elsevier Science Ltd.