We examined 25 patients with thyroid eye disease, using both the STIR
(Short Tau Inversion Recovery) sequence and cine MRI techniques, A num
ber of characteristic features can be seen on the cine MRI. There is m
uscle enlargement with restriction of movement and, in the burnt-out p
hase of the disease, reduced elasticity of the muscles is manifest as
their failure to stretch on eye movement. This is in contrast to the a
ctive phase of the disease, where although the muscles are enlarged, m
uscle stretching is clearly visible. The STIR sequence gives an assess
ment of muscle water content, and hence a high signal is seen in activ
e disease. Combining these techniques is useful in assessing the level
of disease activity in thyroid eye disease, and helps in planning fur
ther management.