K. Hynynen et al., FEASIBILITY OF USING ULTRASOUND PHASED-ARRAYS FOR MRI MONITORED NONINVASIVE SURGERY, IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 43(6), 1996, pp. 1043-1053
The purpose of this paper was to evaluate the in vivo feasibility of u
sing phased arrays for MRI guided ultrasound surgery, Two different ar
ray concepts were investigated: a spherically curved concentric ring a
rray to move the focus along the central iuds and a spherically curved
16 square element array to make the focus larger. Rabbit thigh muscle
s were exposed in vivo in a 1.5 T MRI scanner to evaluate the array pe
rformance. The results showed that both of the arrays performed as exp
ected, and the focus could be moved and enlarged, In addition, adequat
e power could be delivered from the arrays to necrose in vivo muscle t
issue in 10 s, This study was the first implementation of phased array
s for MRI guided ultrasound surgery, The results demonstrate that phas
ed arrays have significant potential for noninvasive tissue coagulatio
n.