TUMOROUS INTRAHEPATIC LYMPHOPROLIFERATIVE DISORDER IN TRANSPLANTED LIVERS

OBJECTIVE. We describe the radiologic findings of lymphoproliferative disorder manifesting as an intrahepatic mass in hepatic transplant rec ipients. Three patients with focal intrahepatic masses due to lymphopr oliferative disorder after transplantation were retrospectively identi fied. Clinical features and radiologic findings in these patients were reviewed in conjunction with pertinent cases from the literature. (Re ports of lymphoproliferative disorder confined to the transplanted liv er have been sporadic.) CONCLUSION. Factors supporting the diagnosis o f tumorous intrahepatic lymphoproliferative disorder include presentat ion 4-12 months after transplantation; portal or periportal location; poorly defined extrahepatic periportal soft tissue; encasement or narr owing of the biliary ducts, hepatic artery, or portal vein; and serolo gic evidence of exposure to Epstein-Barr virus.