OBJECTIVE. Scant information exists on the natural history of a retain
ed wire fragment after needle localization for breast biopsy. We revie
w 10 cases in which wire fragments were present 1.5-11 years after sur
gery. CONCLUSION. Only one patient had symptoms attributed to the reta
ined wire. Position of the wire fragment in the breast remained stable
over time. Our management recommendations include early mammographic
follow-up at 3 and 6 months to reveal stability in asymptomatic patien
ts and excision of fragments in symptomatic patients.