PROXIMAL CUTANEOUS NECROSIS IN ASSOCIATION WITH CHRONIC-RENAL-FAILURE

Authors
WHITTAM LR MCGIBBON DH MACDONALD DM
Citation
Lr. Whittam et al., PROXIMAL CUTANEOUS NECROSIS IN ASSOCIATION WITH CHRONIC-RENAL-FAILURE, British journal of dermatology, 135(5), 1996, pp. 778-781
Citations number
11
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
British journal of dermatology → ACNP
ISSN journal
00070963
Volume
135
Issue
5
Year of publication
1996
Pages
778 - 781
Database
ISI
SICI code
0007-0963(1996)135:5<778:PCNIAW>2.0.ZU;2-6
Abstract
We report two patients with renal failure who developed painful symmet rical ulceration over the proximal thighs and abdominal wall. Histolog ical examination of the ulcerated areas revealed intravascular calcifi cation. This phenomenon has been termed calciphylaxis and is a rare co mplication of renal failure. The pathogenesis is poorly understood, Ho wever, abnormalities of calcium/phosphate metabolism and of coagulatio n are important.