A new feature (AutoSlope) has been introduced that can automatically a
djust the sensor slope based on the chronic activity level of the pati
ent. The algorithm adjusts the slope once per week so that 99% of the
sensor response is maintained between the base rate and 23% of the dif
ference between the programmed Base Rate and the Max Sensor Rate. Offs
ets are available for fine titration of sensor response in individual
patients. The AutoSlope feature was evaluated in 93 patients with DDDR
pacemakers (Trilogy DR+, Pacesetter). Patients were seen at 1, 3, and
6 months for a total of 178 evaluations. At each evaluation, the Auto
Slope value was recorded. Patients then performed a brisk walk at sens
or values equivalent to the AutoSlope value. Desired sensor rate was c
ompared to the rate achieved by AutoSlope for the exercise period. Lon
gterm sensor performance was evaluated by analyzing the sensor histogr
am. AutoSlope provided the desired sensor rate in most patients. Use o
f AutoSlope offsets allows fine titration of rate modulation in indivi
dual patients. Ongoing changes in sensor performance provided by AutoS
lope allow patients to achieve a desired sensor rate from one evaluati
on to another without changes in permanent programmed settings. Progra
mming a low maximum sensor rate may limit sensor response in some pati
ents.