Rheumatic complaints secondary to viral infections are usually brief,
self-limited and nondestructive. They may accompany almost any type of
viral illness, and the arthritic presentation is nonspecific. These m
anifestations are protean, ranging from arthralgia to vasculitis. Ofte
n the cause of the rheumatic complaint remains elusive because of the
prompt resolution of the viral infection; Evaluation for autoimmune di
seases should, be postponed until the symptoms have been present for a
t least six weeks, However, some viral diseases, such as parvovirus, c
hronic hepatitis B virus and hepatitis C virus infections, can produce
long-lasting rheumatic symptoms. Since the arthritis associated with
hepatitis C infection has only recently been recognized, it is importa
nt to search for this association in patients who have atypical rheuma
tic complaints, risk factors for hepatitis and alterations in liver en
zymes, so that an accurate diagnosis can be established and the pathop
hysiology can be better understood.