SEARCHING FOR SIGNALS - MORTALITY AND CARDIOVASCULAR EVENTS IN PUBLISHED RANDOMIZED CENTRAL TRIALS OF NIFEDIPINE IN ISCHEMIC-HEART-DISEASE AND HYPERTENSION

Authors
STASON W SCHMID CH CAUBET JF KUPELNICK B CORY D WHITING G CHALMERS TC ROSS SD
Citation
W. Stason et al., SEARCHING FOR SIGNALS - MORTALITY AND CARDIOVASCULAR EVENTS IN PUBLISHED RANDOMIZED CENTRAL TRIALS OF NIFEDIPINE IN ISCHEMIC-HEART-DISEASE AND HYPERTENSION, Journal of hypertension, 14, 1996, pp. 5-7
Citations number
6
Categorie Soggetti
Cardiac & Cardiovascular System
Journal title
Journal of hypertension → ACNP
ISSN journal
02636352
Volume
14
Year of publication
1996
Supplement
2
Pages
5 - 7
Database
ISI
SICI code
0263-6352(1996)14:<5:SFS-MA>2.0.ZU;2-P
Abstract
Meta-analysis A meta-analysis of published randomized control trials o f nifedipine in hypertension and stable angina pectoris was performed. Results The results suggest a formulation-dependent increased risk of mortality and adverse cardiovascular outcomes for monotherapy use in patients with stable angina pectoris. No increased risk was seen in th e hypertension studies.