THE RADIAL IMMUNODIFFUSION ASSAY FOR PLASMA HISTIDINE-RICH GLYCOPROTEIN (HRG) BASED ON A POLYCLONAL ANTIBODY, SHOWS A DIFFERENT SPECIFICITYTOWARDS THE 2 VARIANTS OF A COMMON AMINO-ACID POLYMORPHISM

Authors
HENNIS BC HOFFMANN JJML KLUFT C
Citation
Bc. Hennis et al., THE RADIAL IMMUNODIFFUSION ASSAY FOR PLASMA HISTIDINE-RICH GLYCOPROTEIN (HRG) BASED ON A POLYCLONAL ANTIBODY, SHOWS A DIFFERENT SPECIFICITYTOWARDS THE 2 VARIANTS OF A COMMON AMINO-ACID POLYMORPHISM, Fibrinolysis, 10, 1996, pp. 133-134
Citations number
4
Categorie Soggetti
Hematology
Journal title
Fibrinolysis → ACNP
ISSN journal
02689499
Volume
10
Year of publication
1996
Supplement
2
Pages
133 - 134
Database
ISI
SICI code
0268-9499(1996)10:<133:TRIAFP>2.0.ZU;2-6
Abstract
Recently, two molecular weight forms of Histidine-rich Glycoprotein ha ve been described which explain 59% of the variation in plasma HRG lev els, Here, we demonstrate that this can partly be ascribed to a differ ence in specificity of the immune assay for HRG towards the two allele s of the polymorphism.